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. 2021 May 12;11:10102. doi: 10.1038/s41598-021-89570-0

Table 2.

Results of histopathological and immunohistochemical analyses of brain and heart samples, with partial and global arbitrary scores.

Animal Brain Total Score Heart
Histology IHC Histology IHC
MI Tu Ty De S100B GFAP Score Score MI Tu MA TnC D
ACA1 0 1 0 0 1 1 3 7 4 0 1 1 1 1
ACA2 0 1 0 0 1 1 3 7 4 0 1 1 1 1
ACA3 0 0 0 0 1 1 2 5 3 0 0 1 1 1
ACA4 1 3 1 1 3 3 12 25 13 1 3 3 3 3
ACA5 1 2 1 1 2 2 9 17 8 0 2 2 2 2
ACA6 1 2 1 1 3 3 11 23 12 1 2 3 3 3
ACA7 0 1 0 0 1 2 4 10 6 0 1 2 1 2
ACA8 0 1 0 0 1 1 3 8 5 0 1 2 1 1
ACA9 1 3 1 1 3 3 12 25 13 1 3 3 3 3
ACA10 1 2 1 1 2 3 10 19 9 0 2 2 2 3
VFCA1 0 0 0 0 1 1 2 5 3 0 0 1 1 1
VFCA2 0 1 0 1 2 1 5 13 8 0 2 2 2 2
VFCA3 0 1 0 0 1 1 3 7 4 0 1 1 1 1
VFCA4 0 2 1 1 3 2 9 18 9 0 2 3 2 2
VFCA5 0 0 0 0 1 1 2 6 4 0 1 1 1 1
VFCA6 0 1 0 0 2 1 4 8 4 0 1 1 1 1
VFCA7 0 0 0 0 2 1 3 7 4 0 1 1 1 1
VFCA8 0 0 0 0 2 1 3 6 3 0 1 1 1 0
VFCA9 0 1 0 0 3 2 6 12 6 0 1 2 1 2
VFCA10 0 2 1 1 3 2 9 18 9 0 2 3 2 2

IHC = Immunohistochemistry; MI = Micro-Infarction; Tu = TUNEL; Ty = Tygrolisis; De = Demyelination; MA = Morphological alterations; GFAP = Glial Fibrillary Acid Pro; TnC = C-Troponin; D = Desmin.

Assigned scores: MI, Ty, De: 0 = absent, 1 = present; MA, 0 = absent, 1 = mild, 2 = moderate, 3 = severe; Tu: 0 = absent, 1 = up to 2%, 2 = up to 5%, 3 = more than 5%; S100B, GFAP, D, TnC: 0 = absent, 1 = mild, 2 = moderate, 3 = severe.