Fig. 1.

Gene expression levels in visceral adipose tissue and liver of the main inflammasome components in obesity and obesity-associated type 2 diabetes. Bar graphs show the mRNA levels of a, g NLRP3, b, h NLRP1, c, i NLRP6, d, j ASC, e, k IL1B and f, l IL18 in visceral adipose tissue and liver, respectively, from lean volunteers (LN), obese NG subjects (OB-NG) and obese patients with T2D (OB-T2D). Bars represent the mean ± SEM. Differences between groups were analyzed by one-way ANOVA followed by Tukey’s tests. *P < 0.05 and **P < 0.01 vs. lean subjects. ^†P < 0.05 vs. OB-NG