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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Adv Ther (Weinh). 2021 Feb 15;4(5):2000278. doi: 10.1002/adtp.202000278

Figure 1.

Figure 1.

The interaction between light and biological tissues. a) The tissue penetration depth of light based on different wavelengths. b) The optical characteristic of different wavelength light when peneetrating tissue. NIR-II fluoruorescence emission exhibits the least scattering and greatest penetration depth when compared to UV/VIS and NIR-I fluorescence emission. c) Reduced scattering coefficients of light in different biological tissues and an intralipid tissue phantom as a function of the wavelength within the 400-1700 nm region. d) Autofluorescence spectra of ex vivo mouse liver (black), spleen (red) and heart tissue (blue) under 808 nm excitating light, which reveals lowest autofluorescence in the region from 1500 nm to 1800 nm. Inset: Autofluorescence spectra at 1300-1800 nm. a-b) Reproduced with permission.[10] Copyright 2018, Royal Society of Chemistry. c-d) Reproduced with permission.[11a] Copyright 2017, Springer Nature.