FIGURE 2.
Profiling of the gut microbiota and pro-inflammatory cytokines in individuals with AML. (A) Pro-inflammatory cytokine concentrations were determined in peripheral blood (n = 6, respectively). (B) Alpha diversity, measured by the inverse Simpson index (n = 6, respectively). (C) Community heatmap analysis at genus level (n = 5, respectively). (D) VIP scores of PLS-DA. VIP scores ranked discriminating power of various taxa between nonADR and ADR groups. Taxon with VIP score of > 1 was considered important in discrimination. (E) Identified reads of B. fragilis in ADR and nonADR patients. (F) Scatterplots of IL-1β levels in periheral blood vs. relative levels of B. fragilis. R 2 and p-values of the regression model are shown on the figures.