Table 2.

Comparison of the changes from baseline in pupillary light reflex parameters after dilute pilocarpine instillation measured by digital pupillometry between the two dosage groups.

	0.0625% group (n = 22)	0.125% group (n = 34)	P value	Bayes factor
Affected eye
ΔMaximal pupil diameter (mm)	1.33 ± 1.02 (0.5, 5.4)	1.95 ± 0.87 (0.2, 4.2)	0.018	3.84
ΔMinimal pupil diameter (mm)	1.22 ± 1.04 (0.4, 5.4)	1.79 ± 0.81 (0.2, 3.9)	0.031	3.11
ΔPupil constriction ratio (%)	1.1 ± 2.4 (− 4, 9)	0.6 ± 3.1 (− 13, 5)	0.462	0.28
ΔLatency (s)	− 0.02 ± 0.18 (− 0.4, 0.5)	− 0.04 ± 0.23 (− 0.4, 0.8)	0.658	0.28
ΔACV (mm/s)	0.19 ± 0.34 (− 0.30, 1.50)	0.28 ± 0.38 (− 0.30, 1.20)	0.362	0.41
ΔMCV (mm/s)	0.28 ± 0.46 (− 0.30, 1.80)	0.33 ± 0.47 (− 0.60, 1.50)	0.703	0.29
ΔADV (mm/s)	0.08 ± 0.14 (− 0.10, 0.50)	0.08 ± 0.13 (− 0.20, 0.30)	0.981	0.27
ΔT75 (s)	− 0.02 ± 1.19 (− 2.5, 1.5)	− 0.16 ± 0.98 (− 1.6, 2.9)	0.635	0.31
Unaffected fellow eye
ΔMaximal pupil diameter (mm)	0.27 ± 0.25 (− 0.2, 0.6)	0.68 ± 0.62 (− 0.3, 2.8)	< 0.01	10.87
ΔMinimal pupil diameter (mm)	0.13 ± 0.23 (− 0.4, 0.5)	0.39 ± 0.46 (− 0.3, 1.9)	0.012	8.04
ΔPupil constriction ratio (%)	1.4 ± 2.8 (− 2, 8)	2.5 ± 4.0 (− 5, 15)	0.233	0.33
ΔLatency (s)	− 0.04 ± 0.02 (− 0.10, 0.0)	− 0.03 ± 0.02 (− 0.10, 0.0)	0.781	0.59
ΔACV (mm/s)	0.23 ± 0.40 (− 0.50, 1.20)	0.36 ± 0.41 (− 0.30, 1.50)	0.249	0.48
ΔMCV (mm/s)	0.42 ± 0.54 (− 0.40, 1.80)	0.50 ± 0.65 (− 0.70, 2.00)	0.625	0.87
ΔADV (mm/s)	0.10 ± 0.13 (− 0.10, 0.30)	0.19 ± 0.23 (− 0.30, 0.60)	0.063	0.31
ΔT75 (s)	0.23 ± 0.94 (− 1.9, 2.4)	0.04 ± 0.82 (− 1.6, 1.7)	0.471	0.29

ACV, Average constriction velocity; ADV, Average dilation velocity; MCV, Maximal constriction velocity; T75, Total time from the peak of constriction to the recovery of the pupil to 75% of maximal pupil diameter; Δ, baseline value minus post-pilocarpine test value.

Data are mean ± standard deviation (min, max) unless otherwise indicated. P values in boldface indicate statistical significance.