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. 2021 May 12;11:10105. doi: 10.1038/s41598-021-89663-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Baseline levels of serum HMGB1. Serum levels of HMGB1 in patients with postoperative acute exacerbation of interstitial lung disease (AE-ILD) were higher than those in patients without (median [IQR]: 5.39 [3.29–11.70] ng/mL vs. 3.55 [2.07–5.62] ng/mL, P = 0.031). Boxes represent the 25th to 75th percentiles; solid lines within the boxes show the median values; whiskers represent the 10th and 90th percentiles; the circles represent outliers. * P < 0.05 using the Mann–Whitney U test. IQR, interquartile range.