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. 2021 May 12;16:88. doi: 10.1186/s13014-021-01808-3

Table 2.

Univariate analysis for PSA failure-free survival after salvage radiotherapy

Variable Hazard ratio (HR) 95% CI p-value

Age, yrs

Cont

1.01 0.95–1.08 0.99

First post- prostatectomy PSA

Cont

1.02 1.0–1.04 0.03

PreRT PSA

Cont

1.05 0.997–1.09 0.06
Fractionation schedule
 66 Gy/33x 1.0
 52.5 Gy/20x 2.2 1.0–4.6 0.03
ADT during RT
 No 1.0
 Yes 3.3 1.2–8.6 0.02

Final pathology Grade Group

Gleason score

Overall p = 0.02
 1 1.0
 2 0.28 0.05–1.45 0.13
 3 1.11 0.25–4.92 0.89
 4 0.38 0.05–2.69 0.33
 5 1.33 0.27–6.65 0.73
pT stage Overall p = 0.03
 T1–T2a 1.0
 T2b–T2c 2.21 0.267–18.42 0.46
 T3–T4 5.23 0.71–38.83 0.11
SVI
 No 1.0
 Yes 1.88 0.91–3.86 0.09
Positive surgical margins
 No 1.0
 Yes 2.04 0.99–4.2 0.052
ECE
 No 1.0
 Yes 1.99 0.99–4.14 0.06

yrs years, cont continuous, PSA prostate-specific antigen, ADT androgen deprivation therapy, RT radiotherapy, SVI seminal vesicle invasion, ECE extracapsular extension