Table 2.
Variable | Hazard ratio (HR) | 95% CI | p-value |
---|---|---|---|
Age, yrs Cont |
1.01 | 0.95–1.08 | 0.99 |
First post- prostatectomy PSA Cont |
1.02 | 1.0–1.04 | 0.03 |
PreRT PSA Cont |
1.05 | 0.997–1.09 | 0.06 |
Fractionation schedule | |||
66 Gy/33x | 1.0 | ||
52.5 Gy/20x | 2.2 | 1.0–4.6 | 0.03 |
ADT during RT | |||
No | 1.0 | ||
Yes | 3.3 | 1.2–8.6 | 0.02 |
Final pathology Grade Group Gleason score |
Overall p = 0.02 | ||
1 | 1.0 | ||
2 | 0.28 | 0.05–1.45 | 0.13 |
3 | 1.11 | 0.25–4.92 | 0.89 |
4 | 0.38 | 0.05–2.69 | 0.33 |
5 | 1.33 | 0.27–6.65 | 0.73 |
pT stage | Overall p = 0.03 | ||
T1–T2a | 1.0 | ||
T2b–T2c | 2.21 | 0.267–18.42 | 0.46 |
T3–T4 | 5.23 | 0.71–38.83 | 0.11 |
SVI | |||
No | 1.0 | ||
Yes | 1.88 | 0.91–3.86 | 0.09 |
Positive surgical margins | |||
No | 1.0 | ||
Yes | 2.04 | 0.99–4.2 | 0.052 |
ECE | |||
No | 1.0 | ||
Yes | 1.99 | 0.99–4.14 | 0.06 |
yrs years, cont continuous, PSA prostate-specific antigen, ADT androgen deprivation therapy, RT radiotherapy, SVI seminal vesicle invasion, ECE extracapsular extension