Abbreviations |
7AAD |
7-Aminoactinomycin D |
Ab |
Antibody |
ACO |
Acyl-CoA oxidase |
ADCC |
Antibody-dependent cellular cytotoxicity |
APC |
Antigen-presenting cells |
CC |
Co-culture |
CD |
Cluster of differentiation |
ChIP |
Chromatin-immunoprecipitation |
CPA/I |
Activatory/inhibitory (immune) checkpoint |
CPS |
Combined positivity score |
CRC |
Colorectal cancer |
EpCAM |
Epithelial cell adhesion molecule |
ERK |
Extracellular signal-regulated kinase |
Fc |
Fragment crystallizable (Ab isotype) |
FC |
Flow cytometry |
FFPE |
Formalin-fixed (agarose) paraffin-embedded |
GW |
GW9662 |
H&E |
Hematoxylin and eosin |
IC |
Inflammatory cell (score) |
IF |
Immunofluorescence |
IFN |
Interferon |
IgG |
Immunoglobulin G |
IHC |
Immunohistochemistry |
IL |
Interleukin |
IRF |
Interferon regulatory factor |
ITC |
Isotype control |
LAK |
Lymphokine-activated killer cells |
LNO2
|
10-Nitrolinoleate |
MEK |
Mitogen-activated protein kinase kinase |
MSI/MSS |
Microsatellite instable/stable |
NK |
Natural killer |
OD |
Optical density |
PBMCs |
Peripheral blood mononuclear cells |
PD1 |
Programmed cell death 1 (PDCD1/CD279) |
PD-L1 |
Programmed cell death 1 ligand 1 (PDCD1LG1/CD274) |
PDO |
Patient-derived (tumor) organoid |
PDIO |
Patient-derived immune organoid |
pio |
Pioglitazone |
PPARγ |
Peroxisome proliferator-activated receptor gamma |
PPRE |
PPARγ-responsive (DNA binding) element |
R/NR |
Responder/non-responder (to LAK) |
RAS |
Rous sarcoma oncogene |
rosi |
Rosiglitazone |
SC |
Single culture |
TPS |
Tumor proportion score |
WB |
Western blot |
WT |
Wild type |