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. 2021 May 5;10(1):1906500. doi: 10.1080/2162402X.2021.1906500
Abbreviations
7AAD 7-Aminoactinomycin D
Ab Antibody
ACO Acyl-CoA oxidase
ADCC Antibody-dependent cellular cytotoxicity
APC Antigen-presenting cells
CC Co-culture
CD Cluster of differentiation
ChIP Chromatin-immunoprecipitation
CPA/I Activatory/inhibitory (immune) checkpoint
CPS Combined positivity score
CRC Colorectal cancer
EpCAM Epithelial cell adhesion molecule
ERK Extracellular signal-regulated kinase
Fc Fragment crystallizable (Ab isotype)
FC Flow cytometry
FFPE Formalin-fixed (agarose) paraffin-embedded
GW GW9662
H&E Hematoxylin and eosin
IC Inflammatory cell (score)
IF Immunofluorescence
IFN Interferon
IgG Immunoglobulin G
IHC Immunohistochemistry
IL Interleukin
IRF Interferon regulatory factor
ITC Isotype control
LAK Lymphokine-activated killer cells
LNO2 10-Nitrolinoleate
MEK Mitogen-activated protein kinase kinase
MSI/MSS Microsatellite instable/stable
NK Natural killer
OD Optical density
PBMCs Peripheral blood mononuclear cells
PD1 Programmed cell death 1 (PDCD1/CD279)
PD-L1 Programmed cell death 1 ligand 1 (PDCD1LG1/CD274)
PDO Patient-derived (tumor) organoid
PDIO Patient-derived immune organoid
pio Pioglitazone
PPARγ Peroxisome proliferator-activated receptor gamma
PPRE PPARγ-responsive (DNA binding) element
R/NR Responder/non-responder (to LAK)
RAS Rous sarcoma oncogene
rosi Rosiglitazone
SC Single culture
TPS Tumor proportion score
WB Western blot
WT Wild type