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. 2021 May 12;4:563. doi: 10.1038/s42003-021-02079-0

Fig. 6. ILCFR are expanded in chronic HIV viral infection in human lymph nodes.

Fig. 6

In a plots shows frequency of ILCFR in human HIV or chronic infection HIV+ lymph nodes. Gated on live cells, CD45+linCD3CD19CD161CD127lo/−. In b the graph shows frequency of ILCFR among CD45+ lymph node cells in both HIV and HIV+ individuals (unpaired, two-tailed nonparametric t-test; ***p = 0.0008; df = 5, 95% CI: (−0.02406 to −0.01140), t = 7.198; Mean ± SD). c shows frequency of total live CD45+ cells in both groups from b. In d the plots show Bcl6 expression in ILCFR in human HIV or HIV+ lymph nodes, gated on CD45+linCD3CD19CD161CD127lo/−CXCR5+CD74+ from the gates in a, and e shows the graph of frequency of Bcl6+ among CD45+ lymph node cells in HIV and HIV+ individuals (unpaired, two-tailed nonparametric t-test; **p = 0.0061; df = 5, 95% CI: (−0.01809 to −0.00504), t = 4.559; Mean ± SD) (2 independent experiments) (n = 3 or 4 biologically independent tonsils per group).