Table 3.

Association of serum IgG4 levels with complicated disease.

	Crude	Model 1a	Model 2b
Elevated serum IgG4	0.44 (0.25–0.8)	0.49 (0.27–0.89)	0.49 (0.26–0.92)
Quartile 1 and quartile 2 of serum IgG4	1.92 (1.29–2.85)	1.82 (1.21–2.74)	1.86 (1.2–2.88)
Quartile 3 of serum IgG4	1.66 (1.05–2.63)	1.59 (1.002–2.52)	1.82 (1.11–2.98)
Quartile 4 of serum IgG4	Reference	Reference	Reference
P for trend	0.001	0.004	0.005
Per-SD increase	0.72 (0.61–0.86)	0.74 (0.62–0.88)	0.74 (0.62–0.89)

Data are odds ratio (95% confidence interval).

^aAdjusted for gender and age.

^bAdjusted for gender, age, disease duration, history of appendectomy and intestinal surgery, disease location, and disease activity.