TABLE 3.

Associations between genetic polymorphisms and the onset of myopia in various genetic models.

Marker	Polymorphisms	Remaining non-myopic		Incident myopia		OR (95% CI)	P	P’
		No.	%	No.	%
rs10760673 (TGFBR1)
	G	223	60.3	251	59.5
	A	147	39.7	171	40.5
Dominant	GG	66	35.7	75	35.5	Reference
	GA or AA	119	64.3	136	64.5	1.007 (0.664, 1.527)	0.974	0.999
Recessive	GG or GA	157	84.9	176	83.4	Reference
	AA	28	15.1	35	16.6	1.115 (0.645, 1.928)	0.696	0.704
Additive	–	–	–	–	–	1.034 (0.774, 1.382)	0.819	0.822
rs7550232 (TGFB2-AS1)
	A	348	94.5	380	90.5
	C	20	5.5	40	9.5
Dominant	AA	164	89.1	171	81.4	Reference
	AC or CC	20	10.9	39	18.6	1.917 (1.069, 3.347)	0.029*	0.025*
Recessive	AA or AC	184	100	209	99.5	Reference
	CC	0	0	1	0.5	–	–	–
Additive	–	–	–	–	–	1.938 (1.092, 3.438)	0.024*	0.022*

OR, odds ratio; CI, confidence interval; P, P-value; P’, P-value adjusted by 10,000 permutations. Adjusted for gender, age, near work time, and outdoor time. * Statistically significant at P < 0.05.