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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Hepatology. 2021 May 8;73(6):2342–2360. doi: 10.1002/hep.31614

Figure 4. Global proteomic profiling of murine MYC-driven HCC.

Figure 4

a. Schematic showing the mouse model of transgenic MYC-HCC. b. Representative H&E and IHC for MYC images from three MYC-HCC tumors demonstrating vascular invasion. c. Heatmap shows the top differentially expressed proteins between MYC-HCC and control liver tissue. d. Expression of known biomarkers of human HCC in murine MYC-driven HCC. e. Top upstream regulators of proteomic changes in MYC-HCC. f. Top biological processes that are dysregulated in the MYC-HCC.