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. 2021 Feb 24;41(8):1699–1715. doi: 10.1523/JNEUROSCI.1237-20.2020

Table 4.

Within-subject RSA results in TPJ using valid trials

Spearman's ρ (mean ± SD)
ppermutation ppermutationb
ASD HC
Neurosynth lTPJ Audience 0.026 ± 0.016*** 0.025 ± 0.014*** 0.848 0.493
Moral context 0.131 ± 0.069*** 0.148 ± 0.054*** 0.403 0.493
Payoff for oneself −0.005 ± 0.008 −0.002 ± 0.007 0.174 0.271
Payoff for association −0.004 ± 0.006 −0.003 ± 0.006 0.413 0.447
rTPJ Audience 0.032 ± 0.025*** 0.024 ± 0.013*** 0.201 0.163
Moral context 0.101 ± 0.047*** 0.150 ± 0.071*** 0.013 0.018
Payoff for oneself −0.004 ± 0.009 −0.003 ± 0.007 0.723 0.311
Payoff for association −0.004 ± 0.010 −0.006 ± 0.009 0.578 0.995
Meta-analysisa lTPJ Audience 0.021 ± 0.019*** 0.022 ± 0.014*** 0.912 0.931
Moral context 0.112 ± 0.079*** 0.100 ± 0.065*** 0.566 0.551
Payoff for oneself −0.002 ± 0.007 0.0005 ± 0.009 0.304 0.472
Payoff for association −0.005 ± 0.005 −0.003 ± 0.007 0.308 0.262
rTPJ Audience 0.025 ± 0.022*** 0.020 ± 0.014*** 0.383 0.230
Moral context 0.066 ± 0.036*** 0.119 ± 0.070*** 0.006 0.002
Payoff for oneself −0.002 ± 0.008 −0.002 ± 0.007 0.900 0.685
Payoff for association −0.003 ± 0.007 −0.003 ± 0.006 0.924 0.400

We excluded trials that did not reach the behavioral criterion (i.e., those with a decision time of <200 ms or longer than the mean ± 3 SDs of that individual) or fMRI criterion (all trials in a run with an excessive head motion: ASD, >5 mm; HC, >3 mm). l, Left; r, right.

aThese masks were spheres with a radius of 10 mm centering on the MNI coordinates based on a recent meta-analysis involving the mentalizing process (peak MNI coordinates: left TPJ/pSTS: −53/−59/20; right TPJ/pSTS: 56/−56/18).

bWe added the standardized age as the covariates to the regression, using the lmPerm package.

***These effects are significantly higher than 0 (i.e., one-sample t test with 5000 permutations; ppermutation < 0.001).