Table 4.
Spearman's ρ (mean ± SD) |
ppermutation | ppermutationb | ||||
---|---|---|---|---|---|---|
ASD | HC | |||||
Neurosynth | lTPJ | Audience | 0.026 ± 0.016*** | 0.025 ± 0.014*** | 0.848 | 0.493 |
Moral context | 0.131 ± 0.069*** | 0.148 ± 0.054*** | 0.403 | 0.493 | ||
Payoff for oneself | −0.005 ± 0.008 | −0.002 ± 0.007 | 0.174 | 0.271 | ||
Payoff for association | −0.004 ± 0.006 | −0.003 ± 0.006 | 0.413 | 0.447 | ||
rTPJ | Audience | 0.032 ± 0.025*** | 0.024 ± 0.013*** | 0.201 | 0.163 | |
Moral context | 0.101 ± 0.047*** | 0.150 ± 0.071*** | 0.013 | 0.018 | ||
Payoff for oneself | −0.004 ± 0.009 | −0.003 ± 0.007 | 0.723 | 0.311 | ||
Payoff for association | −0.004 ± 0.010 | −0.006 ± 0.009 | 0.578 | 0.995 | ||
Meta-analysisa | lTPJ | Audience | 0.021 ± 0.019*** | 0.022 ± 0.014*** | 0.912 | 0.931 |
Moral context | 0.112 ± 0.079*** | 0.100 ± 0.065*** | 0.566 | 0.551 | ||
Payoff for oneself | −0.002 ± 0.007 | 0.0005 ± 0.009 | 0.304 | 0.472 | ||
Payoff for association | −0.005 ± 0.005 | −0.003 ± 0.007 | 0.308 | 0.262 | ||
rTPJ | Audience | 0.025 ± 0.022*** | 0.020 ± 0.014*** | 0.383 | 0.230 | |
Moral context | 0.066 ± 0.036*** | 0.119 ± 0.070*** | 0.006 | 0.002 | ||
Payoff for oneself | −0.002 ± 0.008 | −0.002 ± 0.007 | 0.900 | 0.685 | ||
Payoff for association | −0.003 ± 0.007 | −0.003 ± 0.006 | 0.924 | 0.400 |
We excluded trials that did not reach the behavioral criterion (i.e., those with a decision time of <200 ms or longer than the mean ± 3 SDs of that individual) or fMRI criterion (all trials in a run with an excessive head motion: ASD, >5 mm; HC, >3 mm). l, Left; r, right.
aThese masks were spheres with a radius of 10 mm centering on the MNI coordinates based on a recent meta-analysis involving the mentalizing process (peak MNI coordinates: left TPJ/pSTS: −53/−59/20; right TPJ/pSTS: 56/−56/18).
bWe added the standardized age as the covariates to the regression, using the lmPerm package.
***These effects are significantly higher than 0 (i.e., one-sample t test with 5000 permutations; ppermutation < 0.001).