Spindle and spike rates are inversely related. A, Electrodes used to compute the average spindle rate (red regions) and the summed spike rate for two detection methods (yellow regions for Persyst, red boxes for SpikeNet, based on the montages used for these algorithms). B, C, The spike rate computed with (B) Persyst and (C) SpikeNet is lower in corresponding regions with higher spindle rate. Solid curve indicates the model fit. Dashed curves indicate the 95% CIs.