Figure 8.

Interactive browsing and downloading of data associated with the quantification of neurites and potential synaptic connectivity on www.Hippocampome.org. A, Representative screenshot of a www.Hippocampome.org data matrix. The drop-down menu (light blue box) provides options to display dendritic and axonal lengths, somatic distances, average numbers of potential synapses, numbers of contacts per connected pair, and connection probabilities. Green-outlined box represents the Connection Probabilities tool. Red box highlights the download section for the data. The representative entry in the brown box, enlarged in the dark blue box, corresponds to the somatic distances along the dendrite for a CA1 Radiatum Giant cell in SLM. A1, Bibliographic evidence underlying the reported somatic distance. A1a, Depiction of the dendrites measured to determine the above distance value. A1b, Source figure from which A1a is derived. B, Section of the “number of contacts” matrix. Dark red box highlights the number of contacts between presynaptic Mossy and postsynaptic Basket CCK⁺, whose parcel-specific values are shown in B1. B2, Bibliographic evidence for the selected number of contacts per connected pair and illustration of the neurites isolated in computing the number of contacts for the selected parcel (B2a) and the corresponding source image (B2b). C, Users can download all values from the matrix in comma-spaced-value format. D, The Connection Probabilities tool is used to find connection probabilities and numbers of contacts from user-supplied ultrastructural parameter values for a given pair of neurons. D1, The results are computed for all of the local layers involved in the connection between the two selected neuron types.