Fig. 4.

Expression profiles of HBV splice variants in HBV-transfected Huh7 cells, HBV-infected PHHs and biopsy samples. The heatmaps show the mean percentages of HBV RNAs that were spliced. The RNA-seq libraries that had ≥5 splice variants are shown. The known (SP) and putative (pSP) splice variants were reproducibly detected across the independent biological replicates of HBV-transfected Huh7. Other splice variants are represented with PacBio CCS read names (see Methods). See also Figs S4–S6, Table S1.