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. 2021 Apr 28;12:641210. doi: 10.3389/fphar.2021.641210

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Copyright © 2021 Cocetta, Governa, Borgonetti, Tinazzi, Peron, Catanzaro, Berretta, Biagi, Manetti, Dall’Acqua and Montopoli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HPLC-DAD chromatogram of C. sativa scCO₂ extract. Tentative identification of the main cannabinoids are reported in the Figure. CBDA, cannabidiolic acid; CBGA, cannabigerolic acid; CBD, cannabidiol; CBN, cannabinol; THCA, tetrahydrocannabinolic acid; THC, tetrahydrocannabinol; CBC, cannabichromene. *: identification was confirmed by co-injection with reference standards.