Table 4.
Characteristics of bla CTX-M harbouring E. coli isolates recovered from the two university students of FFUP
|
Student ID |
Sex/ age* |
Isolate ID |
Isolation date |
Resistance profile to β-lactam and non-β-lactam antibiotics† |
ESBL genes |
Other β-lactamases |
Resistance to non-β-lactams genes |
Virulence genes‡ |
Phylogenetic group |
|---|---|---|---|---|---|---|---|---|---|
|
2 |
F/ 21 |
2A |
October 2015 |
AML, PRL, CXM§, CTX, ATM§, CAZ§, TET |
CTX-M group 1 |
TEM, SHV |
tet(A) |
fimH, iutA , traT, cvaC |
B1 |
|
24 |
F/ 22 |
24A |
March 2016 |
AML, PRL, CXM, CTX, CPT |
CTX-M group 9 |
– |
– |
fimH, fyuA, traT |
A |
|
24B|| |
March 2016 |
AML, PRL, CXM, CTX, CPT, TET |
CTX-M group 9 |
TEM |
tet(A) |
fimH, iutA, fyuA, traT |
B1 |
||
|
24C||, ¶ |
October 2016 |
AML, PRL, CXM, CTX, CPT, TET |
CTX-M group 9 |
TEM |
tet(A) |
fimH, iutA, fyuA |
D |
*F, Female.
†AML, amoxicillin; PRL, piperacillin; CXM, cefuroxime; CTX, cefotaxime; ATM, aztreonam; CAZ, ceftazidime; CPT, ceftaroline; TET, tetracycline.
‡fimH - type one fimbriae; iutA - ferric aerobactin receptor; fyuA - yersiniabactin receptor; traT - serum survival associated; cvaC - colicin V; underlined - antibiotic resistance genes and virulence genes transferred in conjugation assay; (-) not detected.
§Isolates with intermediate resistance.
||Colonies with mucoid aspect.
¶Isolate recovered after 5 months of the first detection (October 2016).