Table 2.
Mean (standard deviation) of cardiovascular, urine osmolality, and metabolic measures by Treatment at pre- and post-intervention
| Measure | Pre-intervention | Post-intervention | ||
|---|---|---|---|---|
| Oxytocin | Placebo | Oxytocin | Placebo | |
| Cardiovascular | ||||
| Heart rate (bpm) | 68.33 (11.26) | 67.26 (9.11) | 65.76 (10.69) | 63.76 (11.62) |
| Systolic BP (mmHg) | 134.00 (16.91) | 130.87 (18.43) | 134.24 (16.22) | 129.02 (18.72) |
| Diastolic BP (mmHg) | 75.73 (9.95) | 78.76 (10.43) | 77.35 (11.04) | 78.90 (12.72) |
| Urine-based | ||||
| Osmolality (mOsm/kg) | 591.04 (222.08) | 632.11 (255.51) | 568.55 (221.02) | 599.40 (288.48) |
| Metabolic | ||||
| BUN (mg/dL) | 18.96 (5.80) | 18.41 (7.17) | 18.68 (5.24) | 17.72 (5.35) |
| BUN:Creatinine ratio | 17.96 (4.77) | 18.44 (5.05) | 17.43 (3.78) | 17.63 (5.49) |
| Creatinine (mg/dL) | 1.07 (0.22) | 1.00 (0.28) | 1.07 (0.23) | 1.03 (0.26) |
| eGFR (mL/min/1.73 m2) | 71.77 (16.69) | 78.37 (16.65) | 70.91 (16.17) | 75.88 (16.41) |
| Glucose (mg/dL) | 105.57 (29.09) | 109.60 (42.56) | 108.43 (46.36) | 108.86 (33.02) |
| Potassium (mmol/L) | 4.46 (0.41) | 4.48 (0.49) | 4.53 (0.58) | 4.52 (0.42) |
| Sodium (mmol/L) | 139.70 (2.68) | 140.33 (2.35) | 139.98 (2.50) | 140.98 (2.37) |
BP, blood pressure; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate. Due to equipment issues or errors in data recording, BP and heart rate were missing for three participants at post-intervention (two in the oxytocin and one in the placebo group). There were no significant differences in any outcomes shown here from pre- to post-intervention by group. See information in Table S3 (in Online Resource 3) for numbers of participants represented in each measure from the complete metabolic panel