Table 3.

Added predictive value of NGAL for 90-day transplant-free survival and 90-day survival to prognostic models in cirrhosis

	NGAL	MELD	MELD + NGAL	P value	MELD-Na	MELD-Na + NGAL	P value	CLIF-C ACLF	CLIF-C ACLF + NGAL	P value
Transplant-free survival
C statistic	0.697	0.686	0.713	0.04	0.683	0.708	0.06	0.663	0.697	0.04
Category-free NRI			0.368	0.008		0.349	0.01		0.375	0.007
IDI			0.027	0.02		0.029	0.02		0.036	0.007
Overall survival
C statistic	0.688	0.596	0.662	0.005	0.581	0.653	0.004	0.620	0.675	0.02
Category-free NRI			0.360	0.01		0.388	0.008		0.364	0.01
IDI			0.052	0.007		0.055	0.006		0.056	0.006

ACLF, acute-on-chronic liver failure; CLIF-C ACLF, Chronic Liver Failure Consortium Acute-on-Chronic Liver Failure score; IDI, integrated discrimination increment; MELD, Model for End-Stage Liver Disease; NGAL, neutrophil gelatinase-associated lipocalin; NRI, net reclassification index.