Breast cancer follow-up | Level of evidence | Recommendation strength | |
6.1 | Interval for follow-up | ||
6.1.1 | 1–4 times per year within 5 years of surgery[12] | II | A |
6.1.2 | Annually after 5 years of surgery[12] | II | A |
6.2 | Content of follow-up | ||
6.2.1 | Loco-regional recurrence | ||
a. Ultrasound[12] | II | A | |
b. Mammography[12,29] | I | A | |
6.2.2 | Distant metastasis | ||
a. Screening of distant metastases is not recommended for asymptomatic patients[30,31] | I | A | |
b. Tumor markers | III | C | |
c. CT of chest | III | C | |
d. CT/ ultrasound/MRI of abdomen | III | C | |
e. Bone scan | III | C | |
f. FDG PET/CT | III | C | |
6.2.3 | Complication of surgery | ||
Lymphedema[12] | II | A | |
6.2.4 | Complication of medication | ||
a. Endometrial evaluation during treatment of tamoxifen[12] | II | A | |
b. Assessment of bone mineral density during treatment of aromatase inhibitor[12] | II | A | |
6.2.5 | Guidance of a healthy lifestyle[12] | II | A |
CT: Computed tomography; FDG PET: 18F-deoxyglucose positron emission tomography; MRI: Magnetic resonance imaging.