Table 1.
Thyroid function traits | Consortium or study | Sample size | Population | Year |
FT4 | BHS, CHS, HBCS, KORA, NBS, Rotterdam Study, SardiNIA, SHIP/SHIP-Trend, TwinsUK, ASKLEPIOS, CARLA, EFSOCH, Health2006, SardiNIA2 | 26,089 | Europeans | 2018 |
TSH | BHS, CHS, HBCS, KORA, NBS, Rotterdam Study, SardiNIA, SHIP/SHIP-Trend, TwinsUK, ValBorbera, ASKLEPIOS, CARLA, EFSOCH, Health2006, SardiNIA2 | 27,916 | Europeans | 2018 |
TPOAb | ARIC, BHS, CHS, HBCS, KORA, NBS, RS, SardiNIA, SHIP, TwinsUK, Val Borbera, ASKLEPIOS, CARLA, EFSOCH, Health2006, SardiNIA2 | 18,297 | Trans-ethnic | 2015 |
FT3:FT4 ratio | Weston Area T3/T4 Study (WATTS) cohort, Exeter Family Study of Childhood Health (EFSOCH), Invecchiare in Chianti (InCHIANTI), Depression and Thyroid Disease (DEPTH) | 3065 | Trans-Ethnics | 2008 |
ASKLEPIOS: The Asklepios Study; BHS: The 1994/1995 Busselton health survey; CHS: Cardiovascular Health Study; EFSOCH, Exeter family of childhood health; FT3: Free triiodothyronine; FT4: Free thyroxine; HBCS: Helsinki Birth Cohort Study; NBS: The Nijmegen Biomedical Study; SHIP: Study of Health in Pomerania; SIBLOS: The SIBLing Osteoporosis Study; TPOAb: Thyroid peroxidase antibodies; TSH: Thyrotropin.