Table 3.

Mendelian randomization analysis of lipid metabolism traits.

	FT4		TSH		TPOAb		FT3:FT4 ratio
Items	β ± SE	P	β ± SE	P	β ± SE	P	β ± SE	P
HDL (mg/dL)	−0.013 ± 0.026	0.602	−0.016 ± 0.016	0.331	−0.472 ± 0.496	0.342	0.003 ± 0.067	0.970
LDL (mg/dL)	−0.059 ± 0.044	0.174	0.041 ± 0.018	0.018	−0.649 ± 0.371	0.080	0.170 ± 0.082	0.037
TC (mg/dL)	−0.041 ± 0.037	0.276	0.052 ± 0.017	0.002	−0.930 ± 0.627	0.138	0.160 ± 0.079	0.043
TG (mg/dL)	0.009 ± 0.035	0.801	0.008 ± 0.015	0.610	0.116 ± 0.222	0.602	0.003 ± 0.064	0.969

Results are presented as β ± SE. Causal effects were estimated using instrumental variables. FT3: Free triiodothyronine; FT4: Free thyroxine; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; SE: Standard error; TC: Total cholesterol; TG: Total triglyceride; TPOAb: Thyroid peroxidase antibodies; TSH: Thyrotropin.