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. 2021 May 12;16(5):e0249590. doi: 10.1371/journal.pone.0249590

Table 1. Results of Chi-Squared tests of association between mutational status and demographic and clinicopathological characteristics.

Variable Category Mutation status P-value
KRAS Wild type
n (%) n (%)
Gender Male 74 (50.7%) 72 (49.3%) 0.404
Female 49 (56.3%) 38 (43.7%)
Age, years <50 18 (46.2%) 21 (53.8%) 0.455
51–60 35 (54.7%) 29 (45.3%)
61–70 35 (60.3%) 23 (39.7%)
≥71 35 (48.6%) 37 (51.4%)
T stage T1 1 (33.3%) 2 (66.7%) 0.725
T2 14 (45.2%) 17 (54.8%)
T3 64 (53.3%) 56 (46.7%)
T4 28 (52.8%) 25 (47.2%)
Undocumented 16 (61.5%) 10 (38.5%)
N stage N0 37 (54.4%) 31 (45.6%) 0.533
N1 46 (52.9%) 41 (47.1%)
N2 21 (44.7%) 26 (55.3%)
X 1 (33.3%) 2 (66.7%)
Undocumented 18 (64.3%) 10 (35.7%)
M stage M0 29 (43.9%) 37 (56.1%) 0.092
M1 35 (53.8%) 30 (46.2%)
MX 42 (64.6%) 23 (35.4%)
Undocumented 17 (45.9%) 20 (54.1%)
Location Right colon 40 (66.7%) 20 (33.3%) 0.147
Left colon 24 (46.2%) 28 (53.8%)
Rectum 28 (45.2%) 34 (54.8%)
Colon and rectum 27 (54%) 23 (46%)
Anus 1 (33.3%) 2 (66.7%)
Small intestine 2 (40%) 3 (60%)
Anorectal 1 (100%) 0 (0%)
Prognosis Response to treatment 53 (49.5%) 54 (50.5%) 0.509
No response to treatment 33 (52.4%) 30 (47.6%)