Table 1. Results of Chi-Squared tests of association between mutational status and demographic and clinicopathological characteristics.
Variable | Category | Mutation status | P-value | |
---|---|---|---|---|
KRAS | Wild type | |||
n (%) | n (%) | |||
Gender | Male | 74 (50.7%) | 72 (49.3%) | 0.404 |
Female | 49 (56.3%) | 38 (43.7%) | ||
Age, years | <50 | 18 (46.2%) | 21 (53.8%) | 0.455 |
51–60 | 35 (54.7%) | 29 (45.3%) | ||
61–70 | 35 (60.3%) | 23 (39.7%) | ||
≥71 | 35 (48.6%) | 37 (51.4%) | ||
T stage | T1 | 1 (33.3%) | 2 (66.7%) | 0.725 |
T2 | 14 (45.2%) | 17 (54.8%) | ||
T3 | 64 (53.3%) | 56 (46.7%) | ||
T4 | 28 (52.8%) | 25 (47.2%) | ||
Undocumented | 16 (61.5%) | 10 (38.5%) | ||
N stage | N0 | 37 (54.4%) | 31 (45.6%) | 0.533 |
N1 | 46 (52.9%) | 41 (47.1%) | ||
N2 | 21 (44.7%) | 26 (55.3%) | ||
X | 1 (33.3%) | 2 (66.7%) | ||
Undocumented | 18 (64.3%) | 10 (35.7%) | ||
M stage | M0 | 29 (43.9%) | 37 (56.1%) | 0.092 |
M1 | 35 (53.8%) | 30 (46.2%) | ||
MX | 42 (64.6%) | 23 (35.4%) | ||
Undocumented | 17 (45.9%) | 20 (54.1%) | ||
Location | Right colon | 40 (66.7%) | 20 (33.3%) | 0.147 |
Left colon | 24 (46.2%) | 28 (53.8%) | ||
Rectum | 28 (45.2%) | 34 (54.8%) | ||
Colon and rectum | 27 (54%) | 23 (46%) | ||
Anus | 1 (33.3%) | 2 (66.7%) | ||
Small intestine | 2 (40%) | 3 (60%) | ||
Anorectal | 1 (100%) | 0 (0%) | ||
Prognosis | Response to treatment | 53 (49.5%) | 54 (50.5%) | 0.509 |
No response to treatment | 33 (52.4%) | 30 (47.6%) |