Table 2. Results of Cox regression analysis of the hazard ratios stratified patients’ gender and age, tumour stage and mutational status.

Variable	Category	P-value	HR	95% CI for HR
				Lower	Upper
Gender	Male	0.081	1.77	0.93	3.36
	Female*		1.00
Age	= < 50	0.042	0.41	0.18	0.97
	51–60	0.002	0.26	0.11	0.61
	61–70	0.091	0.54	0.26	1.10
	= 71+ *		1.00
Stage T	T2	0.851	1.09	0.44	2.70
	T3	0.238	0.68	0.35	1.30
	T4*		1.00
Stage N	N0	0.839	0.91	0.369	2.248
	N1	0.417	0.737	0.352	1.541
	N2*		1.00
Stage M	M0	0.256	0.61	0.26	1.44
	M1	0	3.81	1.83	7.93
	Mx*		1.00
Mutation	Wild	0.099	1.68	0.91	3.11
	KRAS*		1.00