Figure 3. Expression of α-SMA. (a) No significant change in α-SMA expression was observed 3 days following MSC administration and a significant decrease occurred after 14 days. Bars represent the mean ± SD. * p < 0.05. Sham (b), Sham-lo (c), Sham-high and control group (d) showed α-SMA positive cells, characterized as spindle-shaped cells with brown cytoplasmic staining (black arrow) in-between hepatocytes, around the central veins, and in the connective tissue septa, between the hepatic lobules (magnification 200´). The high-dose MSC treatment (e) showed lower α-SMA expression than the low-dose MSC treatment (f).