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. Author manuscript; available in PMC: 2021 May 12.
Published in final edited form as: J Am Soc Mass Spectrom. 2020 Apr 2;31(7):1389–1397. doi: 10.1021/jasms.0c00021

Figure 3.

Figure 3.

Results of CIRFESS analysis of the human proteome to assess predicted coverage provided by three common cell surface proteomic enrichment strategies. (A) Natural log of the odds ratio for observed-to-expected frequency of each permutation of the N-glycan consensus motif along with the canonical (S/T) and complete (S/T/C/V) consensus motif. (B) Expected coverage of the different subsets of proteins for each enrichment strategy broken down by which proteins have peptides with predicted extracellular motifs by one or both TM prediction methods. (C) The makeup of SP, TM, and SPC score proteins based on the overlapping coverage of the three individual enrichment strategies. (D) The set of human GPCRs based on expected coverage for enrichment strategy and level of evidence in UniProt.