Table 4.
Cardiac oxidative stress forty-eight hours after doxorubicin injection.
| C (n = 8) | GT (n = 8) | D (n = 6) | DGT (n = 6) | P i | P gt | P d | |
|---|---|---|---|---|---|---|---|
| LH (nmol/g of tissue) | 206 ± 34, 2 | 181 ± 6, 30 | 265 ± 18, 0 | 166 ± 8, 97 | <0,001 | 0,002 | 0,22 |
| CAT (μmol/g of tissue) | 59, 1 ± 10, 5 | 37, 4 ± 7, 01 | 34, 8 ± 7, 18 | 41, 4 ± 5, 24 | 0,002 | 0,30 | <0,001 |
| SOD (nmol/g of tissue) | 17, 1 ± 1, 40 | 16, 7 ± 2, 46 | 13, 4 ± 0, 10 | 11, 2 ± 2, 82 | 0,01 | 0,01 | <0,001 |
| GPx (nmol/g of tissue) | 27, 6 ± 9, 10 | 28, 3 ± 1, 72 | 13, 7 ± 6, 05 | 20, 5 ± 2, 00 | 0,01 | 0,70 | <0,001 |
Groups: C: control; GT: green tea; D: doxorubicin; DGT: doxorubicin+green tea. LH: lipid hydroperoxide; CAT: catalase; SOD: superoxide dismutase; GPx: glutathione peroxidase. Values are expressed in mean ± standard deviation. P value: two-way ANOVA. Pi: P value of interaction; Pgt: P value of green tea; Pd: P value of doxorubicin. We observed the interaction between factors in all the variables evidenced by Pi < 0, 05. LH: D ≠ DGT, D ≠ C. CAT: C ≠ GT, CP ≠ D. SOD: C ≠ GT, C ≠ D, and GT ≠ DGT. GPx: D ≠ DGT, C ≠ D.