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. 2021 May 4;2021:6618874. doi: 10.1155/2021/6618874

Table 5.

Effect of maternal probiotic or synbiotic supplementation during gestation and lactation on mitochondrial-related gene expression in the jejunum and colon of piglets.

Itemsa Dietary treatment SEM P values
Control Antibiotic Probiotic Synbiotic
Jejunum
 mtDNA 1.02 0.997 1.08 0.936 0.0381 0.661
 ATP5A1 1.02b 0.95b 1.17ab 1.43a 0.057 0.014
 ATP5B 1.03b 1.07b 1.20b 1.64a 0.066 0.001
 PGC1α 1.04 0.80 1.18 1.14 0.058 0.110
 TFAM 1.05b 1.21ab 1.28ab 1.51a 0.055 0.016
Colon
 mtDNA 1.06 1.09 0.98 0.80 0.051 0.192
 ATP5A1 1.03 0.75 0.89 0.98 0.042 0.100
 ATP5B 1.02 0.93 1.08 1.06 0.041 0.629
 PGC1α 1.11a 0.65ab 1.16ab 0.60b 0.076 0.008
 TFAM 1.03a 0.71b 0.89ab 0.86ab 0.047 0.106

Data are expressed as means with their SEM (n = 8). Values with different letters in the same row were significantly different (P < 0.05). Values with no letters mean no statistically significant differences among the groups (P > 0.05). amtDNA: mitochondrial DNA; ATP5A1: adenosine triphosphate synthase alpha subunit; ATP5B: adenosine triphosphate synthase β, polypeptide; PGC-1α: peroxisome proliferator-activated receptor γ coactivator-1α; TFAM: mitochondrial transcription factor A.