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. 2020 Jun 6;11(2):210–219. doi: 10.1016/j.jpha.2020.05.014

Table 2.

List of up-regulated oxidative stress regulator proteins and down-regulated oxidative stress-sensitive proteins identified form LNA-treated KPC-KP cells.

Upregulated/downregulated protein Accession no. Protein Fold change
Upregulated protein A6TCW1 Protein RecA 3.31
A6TC47 DNA ligase 1.14
A6TCJ1 Autonomous glycyl radical cofactor 1.05
B5XQ04 Holliday junction ATP-dependent DNA helicase RuvA aa
Downregulated protein B5Y305 50S ribosomal protein L9 −2.24
B5XNB4 30S ribosomal protein S13 −1.52
B5XN86 30S ribosomal protein S7 ba
B5XQC8 50S ribosomal protein L35 ba
A6TES6 Ribosomal protein L11 methyltransferase ba
A6T6T1 Ribosomal protein S12 methylthiotransferase RimO ba
A6TEC2 Ribosomal RNA large subunit methyltransferase G ba
A6T4I7 Ribosomal RNA small subunit methyltransferase A ba
A6TEU2 Ribosomal RNA small subunit methyltransferase B ba
A6TG44 Ribosomal RNA small subunit methyltransferase G ba
A6T4M5 Ribosomal RNA small subunit methyltransferase H ba
A6TCL6 Ribosome maturation factor RimM ba
B5XSX5 Ribosome-binding factor A ba
a

a refers to protein exclusive to LNA-treated KPC-KP cells; b refers to protein exclusive to untreated KPC-KP cells. LNA: linalyl anthranilate; KPC-KP: carbapenemase-producing Klebsiella pneumoniae.