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. 2021 Feb 11;100(6):1537–1546. doi: 10.1007/s00277-021-04447-6

Fig. 2.

Fig. 2

SLAMF7 expression on intramedullary and extramedullary myeloma cells prior to elotuzumab treatment. Giemsa (a, d) and immunohistochemical staining for CD138 (b, e) as well as SLAMF7 (c, f) in the bone marrow (a-c) and in a skin biopsy (d-f) obtained simultaneously prior to elotuzumab treatment (a-f: original magnification ×400; length of the scale bar in d: 50 μm). SLAMF7 shows a strong and consistent expression in the CD138-positive myeloma cells. VCD, bortezomib/cyclophosphamide/dexamethasone; HD-Mel/autoSCT, high-dose melphalan/autologous stem cell transplantation; Len-MT, lenalidomide maintenance; Dara, daratumumab; KRd, carfilzomib/lenalidomide/dexamethasone; BM, bone marrow; EMD, extramedullary disease; VTD-PACE, bortezomib/thalidomide/dexamethasone-cisplatin/adriamycin/cyclophosphamide/etoposide); EloPd, elotuzumab/pomalidomide/dexamethasone; BSC, best supportive care