Table 1.
Clinical characteristics of patients included in the study
| (Likely) damaging allele n = 18 cases |
VUS n = 5 cases |
(Likely) benign n = 8 cases |
No rare HNF1A allele variant n = 289 cases |
|
|---|---|---|---|---|
| Sex, male:female [%] | 28:72 | 40:60 | 50:50 | 52:48 |
| Age at recruitment [years] | 39.7 (17.4) | 54.2 (14.2) | 48.1 (11.2) | 45.6 (9.7) |
| Age at diagnosis [years] | 25.7 (8.6) | 37.3 (9.8) | 36.4 (5.6) | 35.3 (6.5) |
| Diabetes duration [years] | 13.1 (11.6) | 17.3 (10.6) | 9.1 (6.6) | 10.3 (7.7) |
| BMI [kg/m2] | 25.93 (4.75) | 28.34 (6.19) | 34.61 (5.02) | 29.95 (5.76) |
| hsCRP [mg/L] | 0.80 (1.32) | 4.01 (6.30) | 5.21 (5.75) | 3.79 (6.97) |
| HbA1c [%] | 7.7 (1.7) | 6.7 (1.3) | 8.8 (2.1) | 7.6 (1.8) |
| C-peptide [nmol/L] | 0.42 (0.21) | 0.60 (0.57) | 0.81 (0.62) | 0.75 (0.36) |
| Total cholesterol [mmol/L] | 4.75 (1.09) | 4.74 (1.21) | 5.07 (0.88) | 4.79 (1.36) |
| HDL [mmol/L] | 1.37 (0.32) | 1.28 (0.39) | 1.11 (0.23) | 1.17 (0.36) |
| Triglycerides [mmol/L] | 1.24 (0.51) | 1.12 (0.31) | 1.98 (0.96) | 2.15 (1.98) |
Mean values are presented for each group (standards deviation (SD) in parentheses)