Table 2.
Synthetic peptides (spots) of S protein of SARS-CoV-2 and their antibody recognition by the pools of COVID-19 patients' sera.
| Spot (peptide) |
Region | IgG | IgM | IgA |
|---|---|---|---|---|
| 5 | S1A | −/+ | +++/+++ | +/++ |
| 17 | S1C | −/+++ | +++/+++ | −/+++ |
| 18* | S1C | ++/++ | +/++ | +++/++ |
| 20* | S1C | −/− | −/− | ++/− |
| 21 | S1C | +++/+++ | +/+++ | +++/+++ |
| 22 | S1C | −/− | ++/++ | −/− |
| 23 | S1C | +++/− | −/− | −/− |
| 32 | S2 | −/− | +++/+++ | −/++ |
| 34 | S2 | −/− | ++/++ | −/− |
| 37 | S2 | ++/+++ | −/− | −/− |
| 39 | RBD | −/− | +++/+++ | −/− |
| 41 | RBD | −/− | ++/++ | −/− |
| 43 | RBD | −/− | ++/++ | −/++ |
| 49 | RBD | ++/+++ | +++/+++ | −/+++ |
| 52 | RBD | −/− | +++/+++ | −/− |
| 54 | RBD | −/− | −/− | −/++ |
| 62 | RBD | −/− | −/− | −/+++ |
Results Pool 1/Pool 2. “+” denotes positive result; number of “+” signifies relative increase in positive spot intensity in the membrane; “−” denote negative result. Chemical control spots, 61 and 62, are repetition of peptides 54 and 55. ⁎ Peptides of SARS-CoV.