Actin monomer (G-actin binding)
|
Profilin |
Actin nucleotide exchange factor |
Inf2 |
[57] |
Nucleators
|
Arp2/3-complex |
Branched actin networks |
WASP, WAVE |
[38] |
Formins: |
|
|
|
Inf2 (inverted formin 2) |
Unbranched actin structures |
mDia |
[41] |
mDia |
Unbranched actin structures |
Inf2 |
[41] |
Elongation-promoting factors
|
Ena/VASP |
Accelerate elongation and prevent capping |
WAVE, Profilin |
[58] |
Barbed end capping
|
CapZ |
Caps barbed ends of filaments |
Inf2 |
[57] |
Gelsolin |
Severs actin filaments, and caps barbed ends of filaments |
|
[35] |
Crosslinking/Bundling
|
Non-muscle myosin II |
Actin crosslinking and contractile properties |
[59, 60] |
Non-muscle myosin I (Myo1e) |
Actin crosslinking and contractile properties |
[45] |
α-actinin 4 |
Crosslinks actin filaments |
[13] |