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Expression of NLRP3 (a), RAGE (b), HMGB1 (c), CD68 (d), CD11B (e), GFAP (f), and β-amyloid (g) in the hippocampus of Wistar rats 10 days after submission to S. pneumoniae meningitis and treated with RAGE or not. Data were expressed as mean ± SEM, and groups were compared using 2-way ANOVA and Tukey’s test. *p < 0.05 and **p < 0.01 indicate statistical significance compared to the control group; #p < 0.05 indicates statistical significance when compared to the meningitis group (n = 4-5)
