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. 2020 Sep 8;18(1):20–31. doi: 10.1007/s13311-020-00919-1

Table 1.

Differential diagnosis in KLS

Neurological disorders Psychiatric disorders Sleep and medical disorders
Complex partial seizures Alcohol, drugs, and illegal substances intake Post-viral hypersomnia
Severe basilar migraine Depression Narcolepsy
Encephalitis Bipolar disorder (rapid cyclic) IH (with fluctuating sleep times)
Trauma, stroke, or inflammation Seasonal affective disorder Idiopathic recurrent stupor
Tumors within the 3rd ventricle Somatoform disorder Ornityl-carnitine transferase deficit
Brief psychotic episode Intermittent porphyria