Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 22;10(2):853–870. doi: 10.1007/s40121-021-00426-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Fig. 4 — Prevalence of resistance based on in-vitro data (MIC) and in silico prediction (CARD). a Reduced antibiotic susceptibility/resistance rate across ribotypes, clades, and geographic region. Heatmap of proportions of antibiotic-reduced susceptibility/resistant samples for VAN, MET, RIF, and MOX are plotted from top to bottom against ribotypes, color-coded according to clade or continent of sampling; values are shown for proportions > 0.5. b The presence of resistance determinants, identified using the Comprehensive Antibiotic Resistance Database and literature reports, is indicated with a red line. The resistance determinants are indicated by gene name (top) and Antibiotic Resistance Ontology accession number (bottom), and the corresponding antibiotic class and clade are indicated by the color-coded X and Y axes, respectively. The heatmaps represent the proportions of antibiotic-reduced susceptibility/resistant samples; values are shown for proportions > 0.5. EUCAST European Committee on Antimicrobial Susceptibility Testing, MET metronidazole, MIC minimum inhibitory concentration, MOX moxifloxacin, RIF rifaximin, VAN vancomycin