Fig. 1.

Levistolide A treatment rescued the memory deficits and cognitive disorders in APP/PS1 Tg mice. (a) Results of the nest-building test in the APP/PS1 Tg mice. (b) Statistical analysis of nest score for each group of mice. (c) Escape latency in the visible platform and hidden platform test. (d) Path length in the visible platform and hidden platform test. (e) Representative escape routes on the last day of the hidden platform test are shown. (f) Number of times crossing the center region without the platform in 1 min. Data represent the mean ± SD (n > 3), *p < 0.05 compared with the vehicle-treated APP/PS1 Tg mice