Fig. 1.

Flowchart for sample collection design, 3 mg/kg of body weight were first injected intraperitoneally into 12 mSOD1 and 14 WT mice 12 weeks after birth, followed by 1 injection of 0.5 mg/kg at 16 weeks after birth. 12 mSOD1 and 10 WT control mice received phosphate buffer saline following the same schedule. Submandibular collection of blood was performed at 8, 12, 16, and 20 weeks. Mice were euthanized 20 weeks