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Longitudinal hormonal and cytokine result of interest at week 8, 12, 16, and 20 between vehicle-treated WT, R1mab1 WT, vehicle-treated mSOD1, and R1mab1 mSOD1. (a) Lower TNF-α and MCP-1 result between R1 mSOD1 versus Vt mSOD1 at week 16 (p = 0.0068; p = 0.0147, respectively). (b) Insulin result of R1 mSOD1 is lower versus Vt mSOD1 (p = 0.01), R1 WT (p = 0.0181), and Vt WT (p = 0.001)
