Fig. 6.

(a) Summarizes the main highlighted pathways involved in the discrimination of specifically R1Mab1 and vehicle-treated mSOD1 mice, including tyrosine metabolism, arginine and proline metabolism, synthesis and degradation of ketone bodies, and glycine, serine, and threonine metabolism. (b) Summarizes the main highlighted pathways involved in the discrimination of specifically R1Mab1 and vehicle-treated WT mice, including nicotinate and nicotinamide metabolism, starch and glucose metabolism, ascorbate and aldarate metabolism (myo-inositol, d-glucuronate), synthesis and degradation of ketone bodies