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. 2021 Apr 29;8:671353. doi: 10.3389/fnut.2021.671353

Figure 5.

Figure 5

MSG-driven microbiota dysbiosis and damaged gut barrier is attenuated after the quercetin treatment. (A) OTU number and (B) Weighted Unifrac analysis of the control, MSG and MSG+Que group. (C) LEfSe analysis of microbiota in the MSG and MSG+Que group. (D) Microbiota composition and (E) relative abundance of gut flora at the phylum level. (F) The ratio of Firmicutes to Bacteroidetes. (G) Microbiota composition and (H) relative abundance of gut microbiota at the family level. (I) Relative abundance of flora at the genus level. (J) PAS staining and (K) H&E staining of colon tissue. Scale bar: 20 μm. (L) The gene expression of Muc2, ZO-1, and Reg3γ in colon tissues. Data are presented as mean ± SEM, n = 4–6. Data were analyzed by one-way ANOVA followed by post-hoc LSD tests. *p < 0.05, **p < 0.01, ***p < 0.001.