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. 2021 Apr 29;8:671353. doi: 10.3389/fnut.2021.671353

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Copyright © 2021 Zhao, Zhu, Xia, Li, Guo, Zhu and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MSG-induced liver RetSat up-regulation is downregulated after the quercetin treatment. (A) The functional enrichment of DEGs in the MSG and quercetin-treated group. (B) Transcriptome analysis of RetSat in the control, MSG and quercetin-treated group. (C) mRNA expression of liver RetSat. (D) PPAR-α mRNA level in the liver tissue. (E) Retinol content in the liver tissue. FPKM: Fragments per Kilobase Million. Data are presented as mean ± SEM, n = 3–6. Data were analyzed by one-way ANOVA followed by post-hoc LSD tests. *p < 0.05, **p < 0.01, ***p < 0.001.