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. 2021 Apr 29;15:636969. doi: 10.3389/fnins.2021.636969

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Copyright © 2021 Arzalluz-Luque, Cabrera, Skottman, Benguria, Bolinches-Amorós, Cuenca, Lupo, Dopazo, Tarazona, Delás, Carballo, Pascual, Hernan, Erceg and Lukovic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Splicing-related genes with at least one differentially spliced event (p value <0.05) in the Control-RPE vs. Patient-RPE contrast (only genes unique to the RPE contrast are considered). Each event is colored by type (A3, alternative 3′ site; A5, alternative 5′ site; RI, retained intron; SE, skipped exon). dPSI is shown in the y-axis (dPSI < 0: event inclusion favored in control, bottom panel; dPSI > 0: event inclusion favored in patient, upper panel). log2(Fold Change) is shown in the x-axis (FC < 0: gene downregulated in patient, left panel; FC > 0: gene upregulated in patient, right panel).