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. 2021 Apr 29;15:595583. doi: 10.3389/fnins.2021.595583

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Copyright © 2021 Bello-Medina, Hernández-Quiroz, Pérez-Morales, González-Franco, Cruz-Pauseno, García-Mena, Díaz-Cintra and Pacheco-López.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative abundance of bacterial phyla in fecal samples of non-transgenic (NoTg) and Alzheimer’s disease triple-transgenic (3xTg-AD) mice. Sectors in pie charts indicate Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria, TM7, Fusobacteria, and Cyanobacteria phyla as shown by tag colors at the right side of the figure. Abundances of each phylum are shown as percentages beside each sector in the pie charts. “Others” groups phyla with <0.5% relative abundance (Verrucomicrobia, Acidobacteria, Thermotogae, Chloroflexi, Thermi, Gemmatimonadetes, Tenericutes, Euryarchaeota, FBP, Spirochaetes, and Synergistetes). The figure shows data for 3 and 5 months (m) old for NoTg female (A,C) and male mice (E,G) and for 3xTg-AD female (B,D) and male mice (F,H) (Supplementary Tables 1, 2).