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. 2021 May 13;44(2):1047–1069. doi: 10.1007/s11357-021-00375-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Effect of sex and PRS on glutamatergic synapses, synaptic vesicle-associated proteins and stress-/anti-stress-related proteins in the dorsal hippocampus of aged rats. Immunoblot analysis of the biochemical markers of glutamatergic synapses (a, b, c) and synaptic vesicle-associated proteins (d) in synaptosomal fractions collected from the dorsal hippocampus of aged male and female PRS and control (CONT) rats. Immunoblot analysis of the stress-/anti-stress-related proteins in total homogenates (e). Representative immunoblots of GR and MR (f). Immunoblot analysis of aromatase (g). Error bars represent the SEM images. CONT vs PRS * = p < 0.05; ** = p < 0.01; *** = p < 0.001. Males vs females # = p < 0.05; ## = p < 0.0; ### = p<0.001