Global phylogeography and resistome dynamics of carbapenemase-producing
K. pneumoniae
isolates. Each strain is expressed by species name, strain, sequence type, date and country of isolation, and host on the phylogenetic tree shown in (a) under different label colours representative of the country of origin: purple (Italy), green (South Africa), red (China), blue (USA, lemon green (Singapore), orange (UAE), pink (Sweden), turquoise (Thailand), gold (Vietnam), mauve (Malaysia), orange (UK, India or Spain). Members of the same clade (labelled I to XVI) are highlighted with the same colour on the branches. The resistomes of the isolates are shown in (b) under the various clades, with members of the same clade having the same colour as the highlights in the phylogenetic tree in (a); blanks refer to absence of resistance genes and filled sections refer to presence of resistance genes. The phylogeography of the various clades are shown in (c) and most of the clades are concentrated in the USA, Brazil, Europe, UAE, South Africa and South-East Asia.