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. 2020 Nov 10;6(12):mgen000474. doi: 10.1099/mgen.0.000474

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© 2020 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License.

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Fig. 4. — Graphical annotation and comparative alignment of pKP10.8_NDM-1. The resistance genes (light green-coloured arrows), replicase genes (blue-coloured arrows), methyltransferases/restriction endonucleases (rose-coloured arrows), transposons (orange-coloured arrows), insertion sequences (orange-coloured arrows), integrons (red-coloured arrows), resolvases (red-coloured arrows) and recombinases/integrases (red-coloured arrows) on the plasmid are shown with their orientation (direction of arrow), synteny and immediate environment. Other genes with unknown functions are hidden to make the image less cluttered. A circular version of the plasmid is shown in (a). A linear version of the plasmid and its alignment with other similar plasmids (linear arrows with yellow highlighted background) are shown in (b); regions of alignment are shown as red-filled portions whilst non-aligned areas are shown as empty arrows. An enlarged section of the plasmid focusing on the resistance genes (genomic resistance island) are shown in (c) and (d). This plasmid (VXJA01000008) contains NDM-1.