TABLE 1.

Principal RNA modifications and their connection with DNA repair.

Modification	Writers	Readers	Erasers	Connection with DNA repair
m6A	METTL3- METTL14 METTL16 METTL5 ZCCHC4	YTHDF1 YTHDF2 YTHDF3 YTHDC1 YTHDC2	ALKBH5 FTO	Abakir et al., 2020; Zhang et al., 2020a
m1A	TRMT10 TRM6-TRM61 METTL8	YTHDF2	ALKBH1 ALKBH3	Li et al., 2016; Brickner et al., 2020; Svobodová Kovaříková et al., 2020
m5C	NSUN1 to NSUN7 TRDMT1	ALYREF
m3C	METTL2 METTL6 METTL8		ALKBH1 ALKBH3	Brickner et al., 2020
m7G	METTL1 METTL8 WBSCR22 RNMT			Brickner et al., 2020
ADP-ribosylation	PARP10 PARP11 PARP15 TRPT1
A-to-I deamination	ADAR1 ADAR2 ADAT2 ADAT3			Jimeno et al., 2021
ψ	PUS1 to PUS10 PUSL7 RPUSD1 to RPUSD4 DKC1
mcm5U	ELP1 ELP3 ALKBH8 CTU1 CTU2			Fu et al., 2010; Zdzalik et al., 2014