TABLE 1.
Top 15 genes identified by cytoHubba.
| Rank | CytoHubba ranking methods | |||||
| MNC | Degree | EPC | Closeness | Radiality | Betweenness | |
| 1 | COL1A2 | COL1A2 | COL5A2 | COL1A2 | COL1A2 | DCN |
| 2 | COL5A2 | COL5A2 | COL1A2 | COL5A2 | SPARC | WWTR1 |
| 3 | SPARC | DCN | SPARC | SPARC | COL5A2 | COL1A2 |
| 4 | FBN1 | SPARC | COL6A1 | DCN | COL6A1 | TNS1 |
| 5 | DCN | FBN1 | COL6A3 | FBN1 | DCN | SPARC |
| 6 | COL6A1 | COL6A1 | DCN | COL6A1 | FBN1 | CALD1 |
| 7 | COL6A3 | THBS2 | FBN1 | THBS2 | CALD1 | AXL |
| 8 | THBS2 | COL6A3 | THBS2 | COL6A3 | TAGLN | GJA1 |
| 9 | EFEMP2 | CALD1 | CDH11 | CALD1 | TIMP3 | CRYAB |
| 10 | PCOLCE | EFEMP2 | ACTA2 | ACTA2 | ACTA2 | MYL9 |
| 11 | ACTA2 | PCOLCE | EFEMP2 | TIMP3 | THBS2 | ISLR |
| 12 | FSTL1 | ACTA2 | CALD1 | TAGLN | COL6A3 | TIMP3 |
| 13 | CDH11 | TIMP3 | PCOLCE | PCOLCE | FSTL1 | TAGLN |
| 14 | TIMP3 | FSTL1 | TIMP3 | FSTL1 | VIM | VIM |
| 15 | CALD1 | CDH11 | FSTL1 | CDH11 | CDH11 | COL6A1 |
Symbols in bold type were the genes overlapped by six ranking methods in cytoHubba. MNC, maximum neighborhood component; degree, node connect degree; EPC: edge percolated component.